NOVEL SALT OF PELUBIPROFEN, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

The present invention relates to a novel salt of pelubiprofen, and a preparation method therefor and a pharmaceutical composition comprising same. Particularly, the present invention relates to a novel tromethamine salt of pelubiprofen, having stability and solubility remarkably superior to those of...

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Bibliographische Detailangaben
Hauptverfasser:	SOHN, Se-Il, PARK, Sang-Wook, LEE, Won-Il, KIM, Churl-Woo, CHO, Min-Yong, SHIN, Sang-Yun
Format:	Patent
Sprache:	eng ; fre ; kor
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a novel salt of pelubiprofen, and a preparation method therefor and a pharmaceutical composition comprising same. Particularly, the present invention relates to a novel tromethamine salt of pelubiprofen, having stability and solubility remarkably superior to those of pelubiprofen and having reduced gastrointestinal disorder side effects. La présente invention concerne un nouveau sel de pélubiprofène, un procédé de préparation associé et une composition cosmétique le comprenant. En particulier, la présente invention concerne un nouveau sel de trométhamine de pélubiprofène, ayant une stabilité et une solubilité remarquablement supérieures à celles du pélubiprofène et ayant des effets secondaires réduits de troubles gastro-intestinaux. 본 발명은 펠루비프로펜의 신규 염, 이의 제조방법 및 이를 포함하는 약학적 조성물에 관한 것이다. 구체적으로, 펠루비프로펜에 비하여 안정성 및 용해도가 현저히 우수하고 위장장애 부작용이 경감된 신규한 펠루비프로펜 트로메타민 염에 관한 것이다.