CELL CULTURE MEDIUM FOR CULTURING EXTRACELLULAR VESICLES AT HIGH CONCENTRATION AND METHOD FOR PREPARING CONDITIONED MEDIUM CONTAINING HIGH CONCENTRATION OF EXTRACELLULAR VESICLES USING CELL CULTURE MEDIUM

The present invention relates to: a cell culture medium for culturing extracellular vesicles at high concentration, the medium comprising lactoferrin; a method for preparing a conditioned medium containing a high concentration of extracellular vesicles, the method comprising culturing cells in the c...

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Bibliographische Detailangaben
Hauptverfasser: CHANG, Song Sun, LEE, Jung Sun, YOU, Ga Eun, KIM, Jun Ho
Format: Patent
Sprache:eng ; fre ; kor
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Zusammenfassung:The present invention relates to: a cell culture medium for culturing extracellular vesicles at high concentration, the medium comprising lactoferrin; a method for preparing a conditioned medium containing a high concentration of extracellular vesicles, the method comprising culturing cells in the cell culture medium; and use of lactoferrin in preparing a conditioned medium containing a high concentration of extracellular vesicles. La présente invention concerne : un milieu de culture cellulaire pour la culture de vésicules extracellulaires à haute concentration, le milieu comprenant de la lactoferrine ; un procédé de préparation d'un milieu conditionné contenant une concentration élevée de vésicules extracellulaires, le procédé comprenant la culture de cellules dans le milieu de culture cellulaire ; et l'utilisation de la lactoferrine dans la préparation d'un milieu conditionné contenant une concentration élevée de vésicules extracellulaires. 본 발명은 락토페린(lactoferrin)을 포함하는 세포외 소포(extracellular vesicles)를 고농도로 배양하기 위한 세포 배양배지; 세포를 상기 세포 배양배지에서 배양하는 것을 포함하는 세포외 소포를 고농도로 함유하는 조건화 배양액(conditioned medium)의 제조방법; 및 세포외 소포를 고농도로 함유하는 조건화 배양액을 제조하는데 사용하기 위한 락토페린의 용도에 관한 것이다.