DRY MICROPARTICLES
The present invention is directed to pharmaceutical compositions, and in particular to slow release pharmaceutical compositions comprising antibody molecule-loaded polymeric microspheres, in the form of dry microparticles. The dry microparticles, and pharmaceutical compositions comprising said dry m...
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| Format: | Patent |
| Sprache: | eng ; fre |
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| Zusammenfassung: | The present invention is directed to pharmaceutical compositions, and in particular to slow release pharmaceutical compositions comprising antibody molecule-loaded polymeric microspheres, in the form of dry microparticles. The dry microparticles, and pharmaceutical compositions comprising said dry microparticles, are stable during manufacturing and upon storage and demonstrate interesting slow-release characteristics. In addition, the invention relates to methods for preparing said dry microparticles.
La présente invention concerne des compositions pharmaceutiques, et en particulier des compositions pharmaceutiques à libération lente comprenant des microsphères polymères chargées de molécules d'anticorps, sous la forme de microparticules sèches. Les microparticules sèches, et les compositions pharmaceutiques comprenant lesdites microparticules sèches, sont stables pendant la fabrication et lors du stockage et présentent des caractéristiques de libération lente intéressantes. De plus, l'invention concerne des procédés de préparation desdites microparticules sèches. |
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