EXOSOME MICRORNA AS SCHIZOPHRENIA MARKER AND USE THEREOF

Provided are an exosome microRNA as a schizophrenia marker and the use thereof. In particular, provided are the use of reagent materials and/or an instrument device for detecting the level of microRNA in a sample from an individual to be tested in the preparation of a detection system for diagnosing...

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Bibliographische Detailangaben
Hauptverfasser: LI, Xiaowan, WEI, Zexu, CAO, Zongze, YU, Yun, HU, Yang, CHENG, Yong, DU, Yang
Format: Patent
Sprache:chi ; eng ; fre
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Zusammenfassung:Provided are an exosome microRNA as a schizophrenia marker and the use thereof. In particular, provided are the use of reagent materials and/or an instrument device for detecting the level of microRNA in a sample from an individual to be tested in the preparation of a detection system for diagnosing the risk of schizophrenia, wherein the microRNA comprises: hsa-miR-206, hsa-miR-145-5p, hsa-miR-133a-3p, hsa-miR-143-3p, hsa-miR-144-5p, hsa-miR-144-3p, hsa-miR-184, hsa-miR-499a-5p, hsa-miR-3614-5p, hsa-miR-941, hsa-miR-30c-5p, hsa-miR-339-5p, hsa-miR-30b-5p, and/or hsa-miR-6515-5p. The exosome miRNA of the present invention can be used as a biomarker for diagnosing patients with a first episode of schizophrenia. MiARN exosome en tant que marqueur de la schizophrénie et son utilisation. En particulier, l'invention concerne l'utilisation de matériaux réactifs et/ou d'un dispositif d'instrument pour détecter le niveau de miARN dans un échantillon provenant d'un individu à tester dans la préparation d'un système de