MONOCLONAL ANTIBODY THAT BINDS SPECIFICALLY TO GITR

The present invention relates to the field of biotechnology, and particularly to antibodies or their antigen-binding fragments, and to the use thereof. More particularly, the present invention relates to monoclonal antibodies that bind specifically to GITR. The invention also relates to a nucleic ac...

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Hauptverfasser:	GORDEEV, Aleksandr Andreevich, USTIUGOV, Iakov Iurevich, TSYMPILOV, Vladimir Sergeevich, ISHUTINOVA, Anastasia Nikolaevna, KOZLOVA, Olesya Nikolaevna, SOZONOVA, Aleksandra Aleksandrovna, SOLOVYEV, Valery Vladimirovich, AGEEV, Sergei Andreevich, DORONIN, Aleksandr Nikolaevich, ULITIN, Andrei Borisovich, BURNYSHEVA, Ksenia Mihailovna, MITROSHIN, Ivan Vladimirovich, MOROZOV, Dmitry Valentinovich, IVANOV, Roman Alekseevich
Format:	Patent
Sprache:	eng ; fre ; rus
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to the field of biotechnology, and particularly to antibodies or their antigen-binding fragments, and to the use thereof. More particularly, the present invention relates to monoclonal antibodies that bind specifically to GITR. The invention also relates to a nucleic acid that codes for said antibody or for an antigen-binding fragment thereof, an expression vector, a method for producing the antibody, and the use of said antibody for treating diseases or disorders associated with GITR. L'invention se rapporte au domaine des biotechnologies et concerne notamment des anticorps et leurs fragments liant à l'antigène, ainsi que leur utilisation. L'invention concerne plus précisément des anticorps monoclonaux se liant spécifiquement à GITR. L'invention concerne également un acide nucléique codant pour cet anticorps ou un fragment de liaison d'antigène de celui-ci, un vecteur d'expression, un procédé de production d'un anticorps et l'utilisation d'un anticorps pour traiter des maladies ou des troubles associés aux GITR. Реферат Настоящее изобретение относится к области биотехнологии, а именно к антителам или их антигенсвязывающим фрагментам, а также их применению. Более конкретно, настоящее изобретение относится к моноклональным антителам, которые специфически связываются с GITR. Изобретение также относится к нуклеиновой кислоте, кодирующей данное антитело или его антигенсвязывающему фрагменту, вектору экспрессии, способу получения антитела и применению антитела для лечения заболеваний или нарушений, связанных с GITR.