COMPOSITIONS, DEVICES AND METHODS FOR FACTOR VII THERAPY
Described herein are RPE cells engineered to secrete a FVII protein, as well as compositions, pharmaceutical preparations, and implantable devices comprising the engineered RPE cells, and methods of making and using the same for treating a patient with hemophilia or FVII deficiency. L'invention...
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| creator | CARMONA, Guillaume JOHNSTON, Erika Ellen WOTTON, Paul Kevin OBERLI, Matthias Alexander YIN, Zoe HEIDEBRECHT, Richard VEISEH, Omid O'CONNOR, Owen SEWELL, Jared A BEAUREGARD, Michael MILLER, Robert James PERITT, David SMITH, Devyn McKinley BARNEY, Lauren Emily GONZALEZ, Francisco Caballero |
| description | Described herein are RPE cells engineered to secrete a FVII protein, as well as compositions, pharmaceutical preparations, and implantable devices comprising the engineered RPE cells, and methods of making and using the same for treating a patient with hemophilia or FVII deficiency.
L'invention concerne des cellules RPE modifiées pour sécréter une protéine de FVII, ainsi que des compositions, des préparations pharmaceutiques et des dispositifs implantables comprenant les cellules RPE modifiées, et des méthodes de fabrication et d'utilisation de celles-ci pour traiter un patient souffrant d'hémophilie ou d'une déficience du FVII. |
| format | Patent |
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L'invention concerne des cellules RPE modifiées pour sécréter une protéine de FVII, ainsi que des compositions, des préparations pharmaceutiques et des dispositifs implantables comprenant les cellules RPE modifiées, et des méthodes de fabrication et d'utilisation de celles-ci pour traiter un patient souffrant d'hémophilie ou d'une déficience du FVII.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210923&DB=EPODOC&CC=WO&NR=2020198695A8$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210923&DB=EPODOC&CC=WO&NR=2020198695A8$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CARMONA, Guillaume</creatorcontrib><creatorcontrib>JOHNSTON, Erika Ellen</creatorcontrib><creatorcontrib>WOTTON, Paul Kevin</creatorcontrib><creatorcontrib>OBERLI, Matthias Alexander</creatorcontrib><creatorcontrib>YIN, Zoe</creatorcontrib><creatorcontrib>HEIDEBRECHT, Richard</creatorcontrib><creatorcontrib>VEISEH, Omid</creatorcontrib><creatorcontrib>O'CONNOR, Owen</creatorcontrib><creatorcontrib>SEWELL, Jared A</creatorcontrib><creatorcontrib>BEAUREGARD, Michael</creatorcontrib><creatorcontrib>MILLER, Robert James</creatorcontrib><creatorcontrib>PERITT, David</creatorcontrib><creatorcontrib>SMITH, Devyn McKinley</creatorcontrib><creatorcontrib>BARNEY, Lauren Emily</creatorcontrib><creatorcontrib>GONZALEZ, Francisco Caballero</creatorcontrib><title>COMPOSITIONS, DEVICES AND METHODS FOR FACTOR VII THERAPY</title><description>Described herein are RPE cells engineered to secrete a FVII protein, as well as compositions, pharmaceutical preparations, and implantable devices comprising the engineered RPE cells, and methods of making and using the same for treating a patient with hemophilia or FVII deficiency.
L'invention concerne des cellules RPE modifiées pour sécréter une protéine de FVII, ainsi que des compositions, des préparations pharmaceutiques et des dispositifs implantables comprenant les cellules RPE modifiées, et des méthodes de fabrication et d'utilisation de celles-ci pour traiter un patient souffrant d'hémophilie ou d'une déficience du FVII.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLBw9vcN8A_2DPH09wvWUXBxDfN0dg1WcPRzUfB1DfHwdwlWcPMPUnBzdA4BUmGengohHq5BjgGRPAysaYk5xam8UJqbQdnNNcTZQze1ID8-tbggMTk1L7UkPtzfyMDIwNDSwszS1NHCmDhVAAUkKXk</recordid><startdate>20210923</startdate><enddate>20210923</enddate><creator>CARMONA, Guillaume</creator><creator>JOHNSTON, Erika Ellen</creator><creator>WOTTON, Paul Kevin</creator><creator>OBERLI, Matthias Alexander</creator><creator>YIN, Zoe</creator><creator>HEIDEBRECHT, Richard</creator><creator>VEISEH, Omid</creator><creator>O'CONNOR, Owen</creator><creator>SEWELL, Jared A</creator><creator>BEAUREGARD, Michael</creator><creator>MILLER, Robert James</creator><creator>PERITT, David</creator><creator>SMITH, Devyn McKinley</creator><creator>BARNEY, Lauren Emily</creator><creator>GONZALEZ, Francisco Caballero</creator><scope>EVB</scope></search><sort><creationdate>20210923</creationdate><title>COMPOSITIONS, DEVICES AND METHODS FOR FACTOR VII THERAPY</title><author>CARMONA, Guillaume ; JOHNSTON, Erika Ellen ; WOTTON, Paul Kevin ; OBERLI, Matthias Alexander ; YIN, Zoe ; HEIDEBRECHT, Richard ; VEISEH, Omid ; O'CONNOR, Owen ; SEWELL, Jared A ; BEAUREGARD, Michael ; MILLER, Robert James ; PERITT, David ; SMITH, Devyn McKinley ; BARNEY, Lauren Emily ; GONZALEZ, Francisco Caballero</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2020198695A83</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2021</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>CARMONA, Guillaume</creatorcontrib><creatorcontrib>JOHNSTON, Erika Ellen</creatorcontrib><creatorcontrib>WOTTON, Paul Kevin</creatorcontrib><creatorcontrib>OBERLI, Matthias Alexander</creatorcontrib><creatorcontrib>YIN, Zoe</creatorcontrib><creatorcontrib>HEIDEBRECHT, Richard</creatorcontrib><creatorcontrib>VEISEH, Omid</creatorcontrib><creatorcontrib>O'CONNOR, Owen</creatorcontrib><creatorcontrib>SEWELL, Jared A</creatorcontrib><creatorcontrib>BEAUREGARD, Michael</creatorcontrib><creatorcontrib>MILLER, Robert James</creatorcontrib><creatorcontrib>PERITT, David</creatorcontrib><creatorcontrib>SMITH, Devyn McKinley</creatorcontrib><creatorcontrib>BARNEY, Lauren Emily</creatorcontrib><creatorcontrib>GONZALEZ, Francisco Caballero</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CARMONA, Guillaume</au><au>JOHNSTON, Erika Ellen</au><au>WOTTON, Paul Kevin</au><au>OBERLI, Matthias Alexander</au><au>YIN, Zoe</au><au>HEIDEBRECHT, Richard</au><au>VEISEH, Omid</au><au>O'CONNOR, Owen</au><au>SEWELL, Jared A</au><au>BEAUREGARD, Michael</au><au>MILLER, Robert James</au><au>PERITT, David</au><au>SMITH, Devyn McKinley</au><au>BARNEY, Lauren Emily</au><au>GONZALEZ, Francisco Caballero</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>COMPOSITIONS, DEVICES AND METHODS FOR FACTOR VII THERAPY</title><date>2021-09-23</date><risdate>2021</risdate><abstract>Described herein are RPE cells engineered to secrete a FVII protein, as well as compositions, pharmaceutical preparations, and implantable devices comprising the engineered RPE cells, and methods of making and using the same for treating a patient with hemophilia or FVII deficiency.
L'invention concerne des cellules RPE modifiées pour sécréter une protéine de FVII, ainsi que des compositions, des préparations pharmaceutiques et des dispositifs implantables comprenant les cellules RPE modifiées, et des méthodes de fabrication et d'utilisation de celles-ci pour traiter un patient souffrant d'hémophilie ou d'une déficience du FVII.</abstract><oa>free_for_read</oa></addata></record> |
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| title | COMPOSITIONS, DEVICES AND METHODS FOR FACTOR VII THERAPY |
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