SMALL-MOLECULE HYALURONIC ACID OR SALT THEREOF, AND PREPARATION METHOD THEREFOR

SMALL-MOLECULE HYALURONIC ACID OR SALT THEREOF, AND PREPARATION METHOD THEREFOR

Provided are a small-molecule hyaluronic acid or a salt thereof, and a preparation method therefor. Lactobacillus plantarum having culture collection number CGMCC NO. 16836 is fermented to produce a hyaluronidase solution. The hyaluronidase solution enzymatically hydrolyzes a hyaluronic acid or a sa...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
1. Verfasser: HAN, Xiuyun
Format: Patent
Sprache:chi ; eng ; fre
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS BASED THEREON
DERIVATIVES THEREOF
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC MACROMOLECULAR COMPOUNDS
POLYSACCHARIDES
SPIRITS
THEIR PREPARATION OR CHEMICAL WORKING-UP
VINEGAR
WINE
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Provided are a small-molecule hyaluronic acid or a salt thereof, and a preparation method therefor. Lactobacillus plantarum having culture collection number CGMCC NO. 16836 is fermented to produce a hyaluronidase solution. The hyaluronidase solution enzymatically hydrolyzes a hyaluronic acid or a salt thereof having a molecular weight of between 500 kDa and 700 kDA, and an obtained small-molecule hyaluronic acid or a salt thereof has a molecular weight of between 1 kDa and 60 kDa. The small-molecule hyaluronic acid enzymatic hydrolysate is subjected to enzyme inactivation, activated carbon impurity absorption, micropore membrane filtration, and low-temperature spray drying to obtain a small-molecule hyaluronic acid or a salt thereof. The resulting product features high safety, excellent transdermal absorbability, ensures the integrity and bioactivity of the molecular structure, and has broader applications. Acide hyaluronique à petite molécule ou sel correspondant et son procédé de préparation. La présente in