COMPOSITION AND METHODS OF AN ADVANCED THERAPY FOR NEURODEGENERATIVE DISEASES

The present disclosure relates to a hydrogel comprising: hyaluronic acid, and liposomes physically crosslinked to hyaluronic acid, wherein said hydrogel encapsulates a cell type or a plurality of cell types. The hydrogel of the present disclosure shows a positive therapeutic effect in the treatment...

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Bibliographische Detailangaben
Hauptverfasser:	GONÇALVES DOS REIS, Rui Luís, DA COSTA MACHADO FERREIRA, Helena Susana, MELEIRO ALVES DAS NEVES, Nuno João
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ENZYMOLOGY HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present disclosure relates to a hydrogel comprising: hyaluronic acid, and liposomes physically crosslinked to hyaluronic acid, wherein said hydrogel encapsulates a cell type or a plurality of cell types. The hydrogel of the present disclosure shows a positive therapeutic effect in the treatment or therapy of multiple sclerosis. A pharmaceutical composition comprising a therapeutically effective amount of a hydrogel and a pharmaceutically acceptable excipient/carrier are also disclosed. La présente invention concerne un hydrogel comprenant : de l'acide hyaluronique, et des liposomes physiquement réticulés à l'acide hyaluronique, ledit hydrogel encapsulant un type de cellule ou une pluralité de types de cellules. L'hydrogel de la présente invention présente un effet thérapeutique positif dans le traitement ou la thérapie de la sclérose en plaques. L'invention concerne également une composition pharmaceutique comprenant une quantité thérapeutiquement efficace d'un hydrogel et un support/excipient pharmaceutiquement acceptable.