PYRROLO[2,3-D]PYRIMIDINONE COMPOUNDS AS CDK2 INHIBITORS

The present application provides pyrrolo[2,3-d]pyrimidinone (I) inhibitors of cyclin-dependent kinase 2 (CDK2), as well as pharmaceutical compositions thereof, and methods of treating cancer using the same. La présente invention concerne des composés de pyrrolo[2,3-d]pyrimidinone (I) inhibiteurs de...

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Hauptverfasser: SOKOLSKY, Alexander, WINTERTON, Sarah, YAO, Wenqing, WU, Liangxing
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creator SOKOLSKY, Alexander
WINTERTON, Sarah
YAO, Wenqing
WU, Liangxing
description The present application provides pyrrolo[2,3-d]pyrimidinone (I) inhibitors of cyclin-dependent kinase 2 (CDK2), as well as pharmaceutical compositions thereof, and methods of treating cancer using the same. La présente invention concerne des composés de pyrrolo[2,3-d]pyrimidinone (I) inhibiteurs de la kinase 2 dépendante des cyclines (CDK2), ainsi que des compositions pharmaceutiques de ceux-ci, et des procédés de traitement du cancer les utilisant.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PYRROLO[2,3-D]PYRIMIDINONE COMPOUNDS AS CDK2 INHIBITORS
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