PYRROLO[2,3-D]PYRIMIDINONE COMPOUNDS AS CDK2 INHIBITORS

The present application provides pyrrolo[2,3-d]pyrimidinone (I) inhibitors of cyclin-dependent kinase 2 (CDK2), as well as pharmaceutical compositions thereof, and methods of treating cancer using the same. La présente invention concerne des composés de pyrrolo[2,3-d]pyrimidinone (I) inhibiteurs de...

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Bibliographische Detailangaben
Hauptverfasser:	SOKOLSKY, Alexander, WINTERTON, Sarah, YAO, Wenqing, WU, Liangxing
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present application provides pyrrolo[2,3-d]pyrimidinone (I) inhibitors of cyclin-dependent kinase 2 (CDK2), as well as pharmaceutical compositions thereof, and methods of treating cancer using the same. La présente invention concerne des composés de pyrrolo[2,3-d]pyrimidinone (I) inhibiteurs de la kinase 2 dépendante des cyclines (CDK2), ainsi que des compositions pharmaceutiques de ceux-ci, et des procédés de traitement du cancer les utilisant.