COMBINATION TREATMENTS FOR CANCER COMPRISING BELANTAMAB MAFODOTIN AND AN ANTI OX40 ANTIBODY AND USES AND METHODS THEREOF

COMBINATION TREATMENTS FOR CANCER COMPRISING BELANTAMAB MAFODOTIN AND AN ANTI OX40 ANTIBODY AND USES AND METHODS THEREOF

Disclosed herein are combinations of an antigen binding protein that binds BCMA with an antigen binding protein that bind to an immunomodulatory agents, such as PD-1 or OX40, pharmaceutical compositions thereof, uses thereof, and methods of treatment comprising administering said combinations, inclu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: OPALINSKA, Joanna, PAUL, Elaine Marie, JACKSON, Nicola A, STRUEMPER, Herbert, BISWAS, Swethajit
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Disclosed herein are combinations of an antigen binding protein that binds BCMA with an antigen binding protein that bind to an immunomodulatory agents, such as PD-1 or OX40, pharmaceutical compositions thereof, uses thereof, and methods of treatment comprising administering said combinations, including uses in cancer. L'invention concerne des combinaisons d'une protéine de liaison à l'antigène qui fixe BCMA à une protéine de liaison à l'antigène qui se lie à des agents immunomodulateurs, tels que PD-1 ou OX40, des compositions pharmaceutiques correspondantes, des utilisations associées, et des méthodes de traitement comprenant l'administration desdites combinaisons, y compris des utilisations contre le cancer.