ANTI-NALOXONE AND ANTI-NALTREXONE MONOCLONAL ANTIBODIES AND METHODS OF PRODUCTION AND USE THEREOF

Antibodies that specifically bind naloxone or naltrexone are disclosed. Also disclosed are conjugates used in the production of the antibodies, as well as methods of producing the antibodies. Also disclosed are methods of using the antibodies in direct assays for naloxone or naltrexone. Further disc...

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Bibliographische Detailangaben
Hauptverfasser:	TENG, Zhu, DRAGHICI, Bogdan, LEBEDEVA, Tatiana, SMIRNOV, Yuriy, DOMINOWSKI, Allison, MORJANA, Nihmat, MAREEVA, Tatiana, BEDZYK, William, SHARMA, Manoj, YAU, Heungyeung, ZHENG, Yi Feng
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING
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Beschreibung
Zusammenfassung:	Antibodies that specifically bind naloxone or naltrexone are disclosed. Also disclosed are conjugates used in the production of the antibodies, as well as methods of producing the antibodies. Also disclosed are methods of using the antibodies in direct assays for naloxone or naltrexone. Further disclosed are methods of reducing naloxone or naltrexone interference in opiate assays using the antibodies. L'invention concerne des anticorps qui se lient spécifiquement à la naloxone ou à la naltrexone. L'invention concerne également des conjugués utilisés dans la production des anticorps, ainsi que des procédés de production des anticorps. L'invention concerne de plus des procédés d'utilisation des anticorps dans des dosages directs pour la naloxone ou la naltrexone. L'invention concerne en outre des procédés de réduction de l'interférence de la naloxone ou de la naltrexone dans des dosages d'opiacés à l'aide des anticorps.