METHOD FOR PREPARING CALCOBUTROL

The present invention relates to a preparation method for synthesizing highly pure calcobutrol without using highly pure gadobutrol, via the preparation of highly pure butrol through a purification step of butrol which is an intermediate of gadobutrol synthesis. La présente invention concerne un pro...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: KIM, Kyoung Joon, MUN, Bo Hyun, KWON, Hyuk Chul, LIM, Dae Sung
Format: Patent
Sprache:eng ; fre ; kor
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention relates to a preparation method for synthesizing highly pure calcobutrol without using highly pure gadobutrol, via the preparation of highly pure butrol through a purification step of butrol which is an intermediate of gadobutrol synthesis. La présente invention concerne un procédé de préparation permettant de synthétiser du calcobutrol très pur sans utiliser de gadolinium hautement pur, au moyen d'une préparation de butrol très pur par l'intermédiaire d'une étape de purification de butrol qui est un intermédiaire de la synthèse d'oxyde de gadolinium. 본 발명은 고순도의 가도부트롤을 이용하지 않고 가도부트롤의 중간체인 부트롤의 정제공정을 통하여 고순도의 부트롤을 제조하고 고순도 칼코부트롤을 합성하는 제조 방법에 관한 것이다.