MODULATORS OF THE ADENOSINE A2A RECEPTOR

The present invention relates to the compounds of formula (I) and salts, stereoisomers, tautomers, isotopologues, or N-oxides thereof. The present invention is further concerned with the use of such a compounds or salt, stereoisomer, tautomer, isotopologues, or N- oxide thereof as modulators of the...

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Bibliographische Detailangaben
Hauptverfasser:	RAJDA, Anna, WYREBEK, Przemyslaw, FABRITIUS, Charles-Henry, PORTER, Roderick Alan, ZASTAWNA, Magdalena, SZEREMETA-SPISAK, Joanna, GALEZOWSKI, Michal, NOWOGRODZKI, Marcin, WRONOWSKI, Marek, LOZINSKA-RAJ, Iwona, BOBOWSKA, Aneta, DUDEK, Marcelina, SWIRSKI, Mateusz, JANIGA, Anita, STASI, Luigi, REUS, Jacek, OBARA, Alicja
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to the compounds of formula (I) and salts, stereoisomers, tautomers, isotopologues, or N-oxides thereof. The present invention is further concerned with the use of such a compounds or salt, stereoisomer, tautomer, isotopologues, or N- oxide thereof as modulators of the adenosine A2A receptor in the treatment of cancer and a pharmaceutical composition comprising said compounds. La présente invention concerne les composés de formule (I) et des sels, stéréoisomères, tautomères, isotopologues ou N-oxydes de ceux-ci. La présente invention concerne en outre l'utilisation de tels composés ou sels, stéréo-isomères, tautomères, isotopologues ou N-oxydes de ceux-ci en tant que modulateurs du récepteur A2A de l'adénosine dans le traitement du cancer et une composition pharmaceutique comprenant lesdits composés.