TUMOR-TARGETED SUPERAGONISTIC CD28 ANTIGEN BINDING MOLECULES

The present invention relates to tumor targeted superagonistic antigen binding molecules capable of multivalent binding to CD28, methods for their production, pharmaceutical compositions containing these antibodies, and methods of using the same. La présente invention concerne des molécules de liais...

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Bibliographische Detailangaben
Hauptverfasser:	GEORGES, Guy, HOFER, Thomas, KLEIN, Christian, UMAÑA, Pablo, GASSER, Stephan, THOM, Jenny Tosca
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to tumor targeted superagonistic antigen binding molecules capable of multivalent binding to CD28, methods for their production, pharmaceutical compositions containing these antibodies, and methods of using the same. La présente invention concerne des molécules de liaison à l'antigène superagonistes ciblant des tumeurs pouvant se lier de manière multivalente à CD28, des procédés pour leur production, des compositions pharmaceutiques contenant ces anticorps, et leurs procédés d'utilisation.