PROCESSES FOR THE PREPARATION OF SITAGLIPTIN AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF

The present application relates to improved processes for the preparation of Sitagliptin and pharmaceutically acceptable salts thereof. The present application also relates to the improved crystallization process for the preparation of Sitagliptin Phosphate. The present application also relates to t...

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Hauptverfasser: GUVVALA, Venkateshwar Reddy, PERUMAL, Gnanamoorthy, AALLA, Sampath, YARRAGUNTLA, Sesha Reddy, KONDRU, Chinnayya, KANDALA, Sreenadha Charyulu, MANNE, Nagaraju
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present application relates to improved processes for the preparation of Sitagliptin and pharmaceutically acceptable salts thereof. The present application also relates to the improved crystallization process for the preparation of Sitagliptin Phosphate. The present application also relates to the improved crystallization process for the preparation of Sitagliptin Hydrochloride monohydrate. La présente invention concerne un procédé de préparation de Sitagliptin et de ses sels pharmaceutiquement acceptables. La présente invention concerne également un procédé de cristallisation amélioré pour la préparation de phosphate de sitagliptine. La présente invention concerne également un procédé de cristallisation amélioré pour la préparation du chlorhydrate de sitagliptine monohydraté.