COMPOUNDS FOR TREATING DIABETES AND/OR RELATED CONDITIONS

Compounds useful for treating or preventing diabetes and related conditions, and for preventing, inhibiting or reversing amylin-amyloid fibril formation, preventing islets of Langerhans (Beta)-cell death, preventing or reversing the transition from soluble human amylin to insoluble human amylin, pre...

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Bibliographische Detailangaben
Hauptverfasser:	ZHENG, Binbin, DING, Ke, ZHANG, Shaoping, COOPER, Garth James Smith, LI, Zhengqiu, AITKEN, Jacqueline F
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds useful for treating or preventing diabetes and related conditions, and for preventing, inhibiting or reversing amylin-amyloid fibril formation, preventing islets of Langerhans (Beta)-cell death, preventing or reversing the transition from soluble human amylin to insoluble human amylin, preventing and inhibiting or reversing cytotoxic amylin fibril formation. The invention relates to compounds of Formula (I) and compounds of Formula (II): (Formulae (I) and (II)). L'invention concerne des composés utilisables pour traiter ou prévenir le diabète et des états apparentés, et pour prévenir, inhiber ou contrecarrer la formation de fibrilles amyloïdes d'amyline, prévenir la mort cellulaire des îlots de Langerhans (Beta), prévenir ou contrecarrer la transition d'amyline humaine soluble en amyline humaine insoluble, prévenir et inhiber ou contrecarrer la formation de fibrilles d'amyline cytotoxiques. L'invention concerne des composés de formule (I) et des composés de formule (II) : (formules (I) et (II)).