APPLICATION OF LITHIUM O-METHYLANILINE IN CATALYZING HYDROBORATION OF IMINE WITH BORANE

The present invention relates to an application of lithium o-methylaniline, and specifically relates to an application of lithium o-methylaniline in catalyzing hydroboration of imine with borane. A catalyst, borane, and imine are sequentially stirred and thoroughly combined, react for 1-2 hours, and are exposed to the air to terminate the reaction. The solvent in the reaction solution is removed under reduced pressure to obtain borates having different substituents. The disclosed lithium o-methylaniline can catalyze the hydroboration of imine with borane with high activity at room temperature. The amount of catalyst used is 4-5 mol% of the moles of imine, and the yield of the reaction can be 90% or more. When compared with existing catalytic systems, the present invention simply uses lithium o-methylaniline, has mild reaction conditions, and the yield of the borates having different substituents can reach 99% under optimized conditions. La présente invention concerne une utilisation du o-méthylaniline-lithium