APPLICATION OF LITHIUM 2,6-DIMETHYLANILINE IN CATALYZING HYDROBORATION OF IMINE WITH BORANE

The present invention relates to an application of lithium 2,6-dimethylaniline, and specifically relates to an application of lithium 2,6-dimethylaniline in catalyzing hydroboration of imine with borane. A catalyst, borane, and imine are sequentially stirred and thoroughly combined, react for 1-2 hours, and are exposed to the air to terminate the reaction. The solvent in the reaction solution is removed under reduced pressure to obtain borates having different substituents. The disclosed lithium 2,6-dimethylaniline can catalyze the hydroboration of imine with borane with high activity at room temperature. The amount of catalyst used is 4-5 mol% of the moles of imine, and the yield of the reaction can be 90% or more. When compared with existing catalytic systems, the present invention simply uses lithium 2,6-dimethylaniline, has mild reaction conditions, and the yield of the borates having different substituents can reach 99% under optimized conditions. La présente invention concerne une utilisation du 2,6-dim