ANTIBACTERIAL COMPOUNDS AND METHODS OF USE

The present invention generally relates to pyridine derivatives of formula (I) with antibacterial activity, especially anti-tuberculosis activity, and pharmaceutical compositions containing them. Methods of using the compounds to treat bacterial infections, especially tuberculosis infections, are al...

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Bibliographische Detailangaben
Hauptverfasser:	BAELL, Jonathan, BARBARO, Lisa, CHE, Daqing, PRIEBBENOW, Daniel
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention generally relates to pyridine derivatives of formula (I) with antibacterial activity, especially anti-tuberculosis activity, and pharmaceutical compositions containing them. Methods of using the compounds to treat bacterial infections, especially tuberculosis infections, are also described. La présente invention concerne de manière générale des dérivés de pyridine de formule (I) ayant une activité antibactérienne, en particulier une activité anti-tuberculose, et des compositions pharmaceutiques les contenant. L'invention concerne également des procédés d'utilisation des composés pour traiter des infections bactériennes, en particulier des infections tuberculeuses.