OLIGOSACCHARIDE COMPOSITIONS AND METHODS OF USE THEREOF FOR REDUCING AMMONIA LEVELS

OLIGOSACCHARIDE COMPOSITIONS AND METHODS OF USE THEREOF FOR REDUCING AMMONIA LEVELS

Aspects of the disclosure relate to oligosaccharide compositions and methods of making the same. Also provided are methods of using oligosaccharide compositions as microbiome metabolic therapies for reducing ammonia levels and for the treatment of hyperammonemia-related diseases (e.g., urea cycle di...

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Bibliographische Detailangaben
Hauptverfasser: HECHT, Max, LIU, Christopher Matthew, GEREMIA, John M, LIOUBOMIROV, Anastasia
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
COMPOSITIONS BASED THEREON
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
DERIVATIVES THEREOF
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
POLYSACCHARIDES
THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:Aspects of the disclosure relate to oligosaccharide compositions and methods of making the same. Also provided are methods of using oligosaccharide compositions as microbiome metabolic therapies for reducing ammonia levels and for the treatment of hyperammonemia-related diseases (e.g., urea cycle disorders and hepatic encephalopathy). Des aspects de la présente invention concernent des compositions d'oligosaccharides et leurs procédés de production. L'invention concerne également des procédés d'utilisation de compositions d'oligosaccharides en tant que thérapies métaboliques du microbiome pour réduire les niveaux d'ammoniaque et pour le traitement de maladies liées à l'hyperammoniémie (par exemple, les troubles du cycle de l'urée et l'encéphalopathie hépatique).