INJECTABLE SOLUTION HAVING PH 7 AND COMPRISING HUMAN GLUCAGON, AT LEAST ONE IONIC SPECIES, AND AN AMPHIPHILIC COMPOUND BEARING HYDROPHOBIC RADICALS

The invention relates to a composition that is physically stable in the form of an injectable aqueous solution, the pH of which is between 6.0 and 8.0, comprising at least: human glucagon, at least one ionic species, and an amphiphilic compound comprising a hydrophilic backbone HB substituted with a...

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1. Verfasser: DAUTY, Emmanuel
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention relates to a composition that is physically stable in the form of an injectable aqueous solution, the pH of which is between 6.0 and 8.0, comprising at least: human glucagon, at least one ionic species, and an amphiphilic compound comprising a hydrophilic backbone HB substituted with at least one hydrophobic radical -Hy of formula I. L'invention concerne une composition stable physiquement sous forme d'une solution aqueuse injectable, dont le pH est compris entre 6,0 et 8,0, comprenant au moins : du glucagon humain, au moins une espèce ionique et un composé amphiphile comprenant un squelette hydrophile HB, substitué par au moins un radical hydrophobe -Hy de formule I.