COMPOUNDS FOR USE IN THE TREATMENT OF FASCIOLIASIS

The present invention relates to compounds of formula (1a), (1b), (1c), (1d) or (1e) and pharmaceutically acceptable salts or solvates thereof for use in the treatment or prevention of fascioliasis. Some of these compounds are novel per se and also have activity as inhibitors of Schistosoma growth....

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Bibliographische Detailangaben
Hauptverfasser:	GARDNER, John Mark Francis, BELL, Andrew Simon
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to compounds of formula (1a), (1b), (1c), (1d) or (1e) and pharmaceutically acceptable salts or solvates thereof for use in the treatment or prevention of fascioliasis. Some of these compounds are novel per se and also have activity as inhibitors of Schistosoma growth. The invention also relates to pharmaceutical compositions comprising such novel compounds, salts or solvates and to the use of such novel compounds as medicaments, in particular in the treatment or prevention of schistosomiasis, also known as bilharzia. La présente invention concerne des composés de formule (1a), (1b), (1c), (1d) ou (1e) et des sels ou solvates pharmaceutiquement acceptables de ceux-ci destinés à être utilisés dans le traitement ou la prévention de la fasciolose. Certains de ces composés sont nouveaux en soi et ont également une activité en tant qu'inhibiteurs de la croissance de Schistosoma. L'invention concerne également des compositions pharmaceutiques comprenant de tels composés, sels ou solvates et l'utilisation desdits nouveaux composés en tant que médicaments, en particulier dans le traitement ou la prévention de la schistosomiase, également connue sous le nom de bilharzia.