NOVEL HYDROXYPROPYL-β-CYCLODEXTRIN AND PROCESS FOR THE PRODUCTION THEREOF

The present invention relates to a novel hydroxypropyl-β-cyclodextrin (HPβCD) and also to a novel process that is of use for producing same. The invention also relates to the use of this HPβCD as an excipient. The invention also relates to an HPβCD for use thereof as a medicament, and more particula...

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Bibliographische Detailangaben
Hauptverfasser:	BUFFE, Clothilde, WIATZ, Vincent, DELATTRE, Joël
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS POLYSACCHARIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	The present invention relates to a novel hydroxypropyl-β-cyclodextrin (HPβCD) and also to a novel process that is of use for producing same. The invention also relates to the use of this HPβCD as an excipient. The invention also relates to an HPβCD for use thereof as a medicament, and more particularly for the treatment or prevention of diseases or conditions related to cholesterol overload and/or storage and/or accumulation in the tissues, and also the consequences thereof, such as certain central nervous system or cardiovascular system ailments. La présente invention se rapporte à une nouvelle hydroxypropyl-β-cyclodextrine (HPβCD) ainsi qu'à un nouveau procédé utile à sa préparation. L'invention se rapporte également à l'utilisation de cette HPβCD comme excipient. L'invention concerne également une HPβCD pour son utilisation comme médicament, et plus particulièrement pour le traitement ou la prévention de maladies ou conditions liées à une surcharge, et/ou à un stockage, et/ou à l'accumulation de cholestérol dans les tissus, ainsi que leurs conséquences, telles que certaines affections du système nerveux central ou du système cardio-vasculaire.