PRODRUGS OF NALTREXONE, NALMEFENE AND DERIVATIVES THEREOF

A novel structure of an opioid antagonist is provided. One of the exemplary compounds of the present disclosure has the structure of Formula (II). The present disclosure overcomes the discomfort of conventional opioid antagonist due to rapid absorption and improves the patient compliance thereof. L&...

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Bibliographische Detailangaben
Hauptverfasser:	JIANG, Yan-Feng, YANG, Syaulan S, LEE, Kuang Yuan
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	A novel structure of an opioid antagonist is provided. One of the exemplary compounds of the present disclosure has the structure of Formula (II). The present disclosure overcomes the discomfort of conventional opioid antagonist due to rapid absorption and improves the patient compliance thereof. L'invention concerne une nouvelle structure d'un antagoniste opioïde. L'un des exemples de composés selon la présente invention a la structure de formule (II). La présente invention surmonte l'inconfort d'un antagoniste opioïde classique dû à une absorption rapide et améliore l'observance correspondante du patient.