MASP-2 INHIBITORS AND METHODS OF USE

MASP-2 INHIBITORS AND METHODS OF USE

The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds and methods of making and using such compounds. La présente invention concerne, entre autres, des composés ayant une activité inhibitrice de MASP-2, des compositions de tels composé...

Ausführliche Beschreibung

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Hauptverfasser: GOLDSTEIN, Sara Rebecca, KESHIPEDDY, Santosh Kumar, CUTSHALL, Neil S, KHALAF, Juhienah, LITTLE, Thomas L, TSOUNG, Jennifer, KWON, Do Yeon, GAGE, Jennifer Lynn, CICIRELLI, Michael, NGUYEN, Jeremiah H, METZ, Markus, NOLLERT VON SPECHT, Peter Kurt, VADDELA, Sudheer Babu, LEMUS, Robert Huerta, GRUSWITZ, Franz A
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds and methods of making and using such compounds. La présente invention concerne, entre autres, des composés ayant une activité inhibitrice de MASP-2, des compositions de tels composés et des procédés de fabrication et d'utilisation de tels composés.