FOAM FORMULATIONS AND DELIVERY METHODS TO THE BODY

A liquid drug delivery formulation forms a foam when combined with a gas source. The formulation includes water, at least one hydrophilic solvent, at least one surfactant or foaming agent, and a drug particle which is a mixture of a therapeutic agent and an excipient. The formulations are useful for...

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Bibliographische Detailangaben
Hauptverfasser:	BINYAMIN, Gary, PIVA, Guillermo, FELD, Tanhum, KONSTANTINO, Eitan
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TO SURFACES, IN GENERAL ATOMISING APPARATUS DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE NOZZLES PERFORMING OPERATIONS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPRAYING APPARATUS SPRAYING OR ATOMISING IN GENERAL TRANSPORTING
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Beschreibung
Zusammenfassung:	A liquid drug delivery formulation forms a foam when combined with a gas source. The formulation includes water, at least one hydrophilic solvent, at least one surfactant or foaming agent, and a drug particle which is a mixture of a therapeutic agent and an excipient. The formulations are useful for delivering foams to body cavities and lumens, such as the sinuses for treating sinusitis and other conditions. Une formulation d'administration de médicament liquide forme une mousse lorsqu'elle est combinée à une source de gaz. La formulation comprend de l'eau, au moins un solvant hydrophile, au moins un tensioactif ou un agent moussant, et une particule de médicament qui est un mélange d'un agent thérapeutique et d'un excipient. Les formulations sont utiles pour administrer des mousses à des cavités corporelles et à des lumières, telles que les sinus pour traiter la sinusite et d'autres états.