MOLECULAR TYPING OF MULTIPLE MYELOMA AND APPLICATION

Disclosed are molecular typing of multiple myeloma and application thereof. Specifically, disclosed is a product comprising a substance for obtaining or detecting 97 gene expressions in multiple myeloma patients to be detected and an apparatus for operating a multiple myeloma Bayesian classifier. By...

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Bibliographische Detailangaben
Hauptverfasser:	SAMO, Ayaz Ali, LI, Jiuyi, FAN, Xiaolong, LU, Xuzhang
Format:	Patent
Sprache:	chi ; eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Disclosed are molecular typing of multiple myeloma and application thereof. Specifically, disclosed is a product comprising a substance for obtaining or detecting 97 gene expressions in multiple myeloma patients to be detected and an apparatus for operating a multiple myeloma Bayesian classifier. By using the product, the present invention identifies a gene module co-expressed with the MCL1 gene, thereby distinguishing molecular subtypes of multiple myeloma having different prognoses and bortezomib sensitivities. L'invention concerne le typage moléculaire de myélome multiple et une application correspondante. Plus particulièrement, l'invention concerne un produit comprenant une substance pour obtenir ou détecter 97 expressions géniques chez des patients atteints du myélome multiple à détecter et un appareil pour faire fonctionner un classifieur bayésien de myélome multiple. Par l'utilisation du produit, la présente invention identifie un module de gène coexprimé avec le gène MCL1, ce qui permet de distinguer