GEMCITABINE AMPHIPHILE PRODRUGS

The present invention relates to improved prodrugs, and compositions thereof. In particular, it relates to amphiphilic gemcitabine prodrugs or amphiphilic prodrugs of other biologically active molecules with the capacity to make liquid crystalline nanostructured nanoparticles, and uses thereof to tr...

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Hauptverfasser: GONG, Xiaojuan, SMITH, Ross Cyril, MOGHADDAM, Minoo Jalili
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creator GONG, Xiaojuan
SMITH, Ross Cyril
MOGHADDAM, Minoo Jalili
description The present invention relates to improved prodrugs, and compositions thereof. In particular, it relates to amphiphilic gemcitabine prodrugs or amphiphilic prodrugs of other biologically active molecules with the capacity to make liquid crystalline nanostructured nanoparticles, and uses thereof to treat animals, including humans. La présente invention concerne des promédicaments améliorés et des compositions de ceux-ci. En particulier, l'invention concerne des promédicaments de gemcitabine amphiphiles ou des promédicaments amphiphiles d'autres molécules biologiquement actives ayant la capacité de fabriquer des nanoparticules nanostructurées cristallines liquides, et leurs utilisations pour traiter des animaux, y compris des êtres humains.
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subjects CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
title GEMCITABINE AMPHIPHILE PRODRUGS
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