GEMCITABINE AMPHIPHILE PRODRUGS

The present invention relates to improved prodrugs, and compositions thereof. In particular, it relates to amphiphilic gemcitabine prodrugs or amphiphilic prodrugs of other biologically active molecules with the capacity to make liquid crystalline nanostructured nanoparticles, and uses thereof to tr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	GONG, Xiaojuan, SMITH, Ross Cyril, MOGHADDAM, Minoo Jalili
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	The present invention relates to improved prodrugs, and compositions thereof. In particular, it relates to amphiphilic gemcitabine prodrugs or amphiphilic prodrugs of other biologically active molecules with the capacity to make liquid crystalline nanostructured nanoparticles, and uses thereof to treat animals, including humans. La présente invention concerne des promédicaments améliorés et des compositions de ceux-ci. En particulier, l'invention concerne des promédicaments de gemcitabine amphiphiles ou des promédicaments amphiphiles d'autres molécules biologiquement actives ayant la capacité de fabriquer des nanoparticules nanostructurées cristallines liquides, et leurs utilisations pour traiter des animaux, y compris des êtres humains.