OXIDIZED BIS(3-INDOLYL)METHANES AND USES THEREOF

Disclosed herein are compounds capable of inducing apoptosis through promoting Nur77 interaction with Bcl-2 and through modulating mitochondrial activities. Also disclosed herein are compositions and methods using these compounds and compositions. Nur77 is a key regulator of Bcl-2 activities and is...

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Bibliographische Detailangaben
Hauptverfasser: SU, Ying, CAO, Xihua, ZENG, Zhiping, DAWSON, Marcia, TU, Xuhuang, ZHANG, Xiao-kun, CHEN, Xiaohui
Format: Patent
Sprache:eng ; fre
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