PEPTIDE SUBSTRATES FOR PAPAIN FAMILY CYSTEINE PEPTIDASES

The invention relates to the field of bioorganic chemistry and concerns novel substrates for determining the enzymatic activity of peptidases. A compound of general formula (1) A-Xaa-Gln-B is proposed as a highly specific and selective substrate for cysteine peptidases of the papain family. The subs...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	ELPIDINA, Elena Nikolaevna, DVORYAKOVA, Elena Aleksandrovna, SOKOLENKO, Mykola Ivanovich, TERESHCHENKOVA, Valeriia Feliksovna, BELOZERSKIY, Mikhail Andreevich, PHILIPPOVA, Irina Yurievna, DUNAEVSKY, Yakov Efimovich, LOBANOVA, Anna Olegovna
Format:	Patent
Sprache:	eng ; fre ; rus
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention relates to the field of bioorganic chemistry and concerns novel substrates for determining the enzymatic activity of peptidases. A compound of general formula (1) A-Xaa-Gln-B is proposed as a highly specific and selective substrate for cysteine peptidases of the papain family. The substrates are resistant to hydrolysis by trypsin-like peptidases. L'invention concerne le domaine de la chimie bio-organique et concerne de nouveaux substrats pour déterminer l'activité oxydante des peptidases. Le composé ayant la formule (1) A-Xaa-Gln-B est proposé en tant que substrat hautement spécifique et sélectif pour les peptidases cystéiniques de la famille de papaïne. Les substrats sont stables vis-à-vis de l'hydrolyse par des peptidases de type trypsine. Изобретение относится к области биоорганической химии и касается новых субстратов для определения ферментативной активности пептидаз. Соединение общей формулы (1) A-Xaa-Gln-B предлагается в качестве высокоспецифичного и селективного субстрата для цистеиновых пептидаз семейства папаина. Субстраты устойчивы к гидролизу трипсиноподобными пептидазами.