AZACYANINE DYES AND USE THEREOF

The application provides fluorescent dyes, which are cyanine dyes that incorporate additional aza moieties in the indolenium heterocycles and/or in the methine chains connecting them. Symmetrical and unsymmetrical chemically reactive azacyanine dyes are described for conjugation, as well as their bi...

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Bibliographische Detailangaben
Hauptverfasser:	MORALES MORALES, Alma Rosa, SINGH, Rajendra, SINISI, Riccardo, GOUN, Elena
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ADHESIVES CHEMISTRY DYES HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES LAKES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MISCELLANEOUS APPLICATIONS OF MATERIALS MISCELLANEOUS COMPOSITIONS MORDANTS NATURAL RESINS ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES PAINTS PHYSICS POLISHES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING
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Beschreibung
Zusammenfassung:	The application provides fluorescent dyes, which are cyanine dyes that incorporate additional aza moieties in the indolenium heterocycles and/or in the methine chains connecting them. Symmetrical and unsymmetrical chemically reactive azacyanine dyes are described for conjugation, as well as their bioconjugates for in-vitro and in-vivo assays and fluorescence imaging. L'invention concerne des colorants fluorescents, qui sont des colorants de cyanine qui incorporent des fractions aza supplémentaires dans les hétérocycles d'indolénium et/ou dans les chaînes de méthine les reliant. L'invention concerne des colorants d'azacyanine chimiquement réactifs symétriques et asymétriques pour conjugaison, ainsi que leurs bioconjugués pour des dosages in vitro et in vivo et une imagerie par fluorescence.