STABLE AQUEOUS ANTI-TAU ANTIBODY FORMULATIONS

The present disclosure provides stable, aqueous, buffered compositions comprising a high concentration of ABBV-8E12, such as a stable, aqueous buffered composition including ABBV-8E12 at a concentration of about 100 mg/ml, at least one buffer, an excipient, a surfactant, and optionally an antioxidan...

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Bibliographische Detailangaben
Hauptverfasser:	HÜLSMEYER, Martin, RINN, Christine, RIED, Christian, SIEDLER, Michael, SCHÄKER-THEOBALD, Kathrin, KALETA, Katharina, MEYER, Tanja, ANGSTENBERGER, Jonas, WILBERTZ, Axel, APPENZELLER, Kerstin
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present disclosure provides stable, aqueous, buffered compositions comprising a high concentration of ABBV-8E12, such as a stable, aqueous buffered composition including ABBV-8E12 at a concentration of about 100 mg/ml, at least one buffer, an excipient, a surfactant, and optionally an antioxidant. La présente invention concerne des compositions tamponnées, aqueuses, stables comprenant une concentration élevée de ABBV-8E12, telle qu'une composition tamponnée, aqueuse, stable, comprenant de l'ABBV-8E12 à une concentration d'environ 100 mg/ml, au moins un tampon, un excipient, un tensioactif, et éventuellement un antioxydant.