CD73 INHIBITORS

The present invention provides 5-[5]-[2-cycloa Ikyl ]-6-pyridazin-3-yl ]- IH-pyrimidine-2,4-dione compounds, or pharmaceutically acceptable salts thereof, that inhibit the activity of CD73 and are useful in treating cancer. (Formula (I)) La présente invention concerne des composés de 5- [5]- [2-cycl...

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Bibliographische Detailangaben
Hauptverfasser:	WANG, Yan, ZHAO, Genshi, HOWELL, Jennifer Marie, DALLY, Robert Dean, HEINZ, Lawrence Joseph II, GARCIA PAREDES, Maria Cristina, NJOROGE, Frank George
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides 5-[5]-[2-cycloa Ikyl ]-6-pyridazin-3-yl ]- IH-pyrimidine-2,4-dione compounds, or pharmaceutically acceptable salts thereof, that inhibit the activity of CD73 and are useful in treating cancer. (Formula (I)) La présente invention concerne des composés de 5- [5]- [2-cycloaIkyl]-6-pyridazin-3-yl]-1H-pyrimidine -2,4-dione, ou des sels pharmaceutiquement acceptables de ceux-ci, qui inhibent l'activité de CD73 et sont utiles dans le traitement du cancer. (Formule (I))