METHOD AND KIT FOR THE CLASSIFICATION OF THYROID NODULES

The present invention describes a method and kit for the classification of thyroid nodules, allowing a more precise identification of the type of thyroid nodule, as being malignant, benign or a subclassification, comprising at least one step of measuring the expression level of at least one normaliz...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	SANTOS, Marcos Tadeu Dos, GAMA, Ricardo Ribeiro, CARVALHO, André Lopes, SILVA, Eduardo Caetano Albino Da, BUZOLIN, Ana Lígia, DUFLOTH, Rozany Mucha
Format:	Patent
Sprache:	eng ; fre ; por
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention describes a method and kit for the classification of thyroid nodules, allowing a more precise identification of the type of thyroid nodule, as being malignant, benign or a subclassification, comprising at least one step of measuring the expression level of at least one normalizing microRNA and at least one discriminating microRNA and at least one step of correlation between the expression level of at least one normalizing microRNA and at least one discriminating microRNA. The present invention pertains to the fields of Genetics and Molecular Biology. La présente invention concerne un procédé et une trousse pour la classification de nodules thyroïdiens, permettant une identification plus précise du type de nodule thyroïdien, soit malin, bénin ou relevant de sous-classifications, comprenant au moins une étape de mesure du niveau d'expresion d'au moins un micro-ARN normalisateur et d'au moins un micro-ARN discriminateur, et au moins une étape de mise en corrélation entre le niveau d'expression d'au moins un micro-ARN normalisateur et d'au moins un micro-ARN discriminateur. La présente invention relève des domaines de la génétique et de la biologie moléculaire. A presente invenção descreve um método e um kit para classificação de nódulos de tireoide que permite uma identificação mais precisa do tipo de nódulo da tireoide, sendo maligno, benigno ou subclassificações, compreendendo pelo menos uma etapa de medição do nível de expressão de pelo menos um microRNA normalizador e pelo menos um microRNA discriminador e pelo menos uma etapa de correlação entre o nível de expressão de pelo menos um microRNA normalizador e pelo menos um microRNA discriminador. A presente invenção se situa nos campos da Genética e Biologia Molecular.