PHARMACOLOGICAL FORMULATION COMPRISING CYCLO (HIS-PRO) AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING DIABETES MELLITUS

The present invention relates to a pharmacological formulation comprising cyclo(His-Pro) as an effective ingredient for preventing or treating diabetes mellitus. More particularly, the present invention exhibits the effect of lowering a glycated hemoglobin (HbA1c) level in blood and further alleviat...

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Bibliographische Detailangaben
Hauptverfasser:	KIM, Kyong-Tai, SONG, Moon Ki, LEE, Heon Jong, LEE, In-Kyu, OLMSTEAD, Kay, JUNG, Hoe-Yune
Format:	Patent
Sprache:	eng ; fre ; kor
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a pharmacological formulation comprising cyclo(His-Pro) as an effective ingredient for preventing or treating diabetes mellitus. More particularly, the present invention exhibits the effect of lowering a glycated hemoglobin (HbA1c) level in blood and further alleviating leptin resistance. In addition, the present invention relates to a pharmacological formulation for prevention or treatment of diabetes mellitus, wherein the pharmacological formulation comprises cyclo(His-Pro) and zinc and is administered once a day. La présente invention concerne une formulation pharmacologique comprenant du cyclo(His-Pro) en tant que principe actif pour la prévention ou le traitement du diabète sucré. Plus particulièrement, la présente invention présente l'effet d'abaisser le taux d'hémoglobine glyquée (HbA1c) dans le sang et d'atténuer davantage la résistance à la leptine. De plus, la présente invention concerne une formulation pharmacologique pour la prévention ou le traitement du diabète sucré, la formulation pharmacologique comprenant du cyclo(His-Pro) et du zinc et étant administrée une fois par jour. 본 발명은 시클로-히스프로를 유효성분으로 함유하는 당뇨병 예방 또는 치료용 약제학적 제제에 관한 것이다. 구체적으로, 본 발명은 혈중 당화혈색소(HbA1c)의 농도를 낮추고, 나아가 렙틴 저항성을 개선하는 효과를 갖는다. 또한, 본 발명은 시클로-히스프로 및 아연을 포함하고, 1일 1회 투여하는 것을 특징으로 하는 당뇨병 예방 또는 치료용 약제학적 제제에 관한 것이다.