ANTIBODIES BINDING CTLA-4 AND USES THEREOF

Disclosed are isolated monoclonal antibodies, comprising a CD152-binding domain, wherein the antibodies bind specifically to human CD152. Methods of making and using the antibodies to treat diseases including cancers and autoimmune diseases are also provided. L'invention concerne des anticorps...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	DRABEK, Dubravka, SHEN, Yuqiang, HE, Yun, VAN HAPEREN, Marinus (Rien), GAN, Xin, RONG, Yiping, ZHAO, Jiuqiao, JANSSENS, Rick, GROSVELD, Frank
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Disclosed are isolated monoclonal antibodies, comprising a CD152-binding domain, wherein the antibodies bind specifically to human CD152. Methods of making and using the antibodies to treat diseases including cancers and autoimmune diseases are also provided. L'invention concerne des anticorps monoclonaux isolés, comprenant un domaine de liaison à CD152, les anticorps Se liant spécifiquement à CD152 humain. L'invention concerne également des procédés de fabrication et d'utilisation des anticorps pour traiter des maladies comprenant des cancers et des maladies auto-immunes.