PHARMACEUTICAL COMPOSITION COMPRISING FIMASARTAN

The present invention relates to a pharmaceutical composition for preventing or treating an angiotensin 2 receptor-related disease, comprising: fimasartan, a pharmaceutically acceptable salt thereof, or a hydrate or solvate thereof; and a soluble polymer. The pharmaceutical composition according to...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: HWANG, Yong Youn, SHIN, Dong Chul, KIM, Myung Sic
Format: Patent
Sprache:eng ; fre ; kor
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention relates to a pharmaceutical composition for preventing or treating an angiotensin 2 receptor-related disease, comprising: fimasartan, a pharmaceutically acceptable salt thereof, or a hydrate or solvate thereof; and a soluble polymer. The pharmaceutical composition according to the present invention increases the solubility of fimasartan and increases the elution thereof and thereby improves the bioavailability thereof. La présente invention concerne une composition pharmaceutique permettant de prévenir ou de traiter une maladie liée au récepteur de l'angiotensine 2, comprenant : du fimasartan, un sel pharmaceutiquement acceptable de celui-ci, ou un hydrate ou un solvate de celui-ci ; et un polymère soluble. La composition pharmaceutique selon la présente invention augmente la solubilité du fimasartan et augmente son élution et améliore ainsi sa biodisponibilité. 본 발명은 피마살탄(fimasartan), 이의 약제학적으로 허용가능한 염, 이의 수화물 또는 용매화물; 및 가용성 고분자를 포함하는 안지오텐신-2-수용체 관련 질환의 예방 또는 치료용 약학적 조성물에 관한 것이다. 본 발명에 따른 약학적 조성물은 피마살탄의 용해도를 증가시키고, 용출을 증가시켜 생체 이용률을 개선시킨다.