PROGNOSTIC METHODS FOR ANTI-TNFA TREATMENT

Methods of determining suitability of a subject to be treated with anti-TNFα therapy comprising measuring blood TREM1 levels or intestinal plasma cell number, intestinal inflammatory macrophage number or intestinal CCL7 or CCR2 levels are provided. Kits for doing same are also provided. L'inven...

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Hauptverfasser:	GAUJOUX, Renaud Gilles, STAROVETSKY, Elina, BAR YOSEPH, Haggai, MAIMON, Naama, VAINBERG, Shiran, SHEN-ORR, Shai S, CHOWERS, Yehuda, PRESSMAN, Sigal
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Methods of determining suitability of a subject to be treated with anti-TNFα therapy comprising measuring blood TREM1 levels or intestinal plasma cell number, intestinal inflammatory macrophage number or intestinal CCL7 or CCR2 levels are provided. Kits for doing same are also provided. L'invention concerne des méthodes de détermination de l'adéquation d'un sujet à être traité avec une thérapie anti-TNFα consistant à mesurer des niveaux de TREM1 sanguin ou le nombre de plasmocytes intestinaux, le nombre de macrophages inflammatoires intestinaux ou les niveaux de CCL7 ou de CCR2 intestinaux. L'invention concerne également des kits pour mettre en œuvre celles-ci.