PHARMACEUTICAL COMPOSITIONS AND DOSAGE FORMS

PHARMACEUTICAL COMPOSITIONS AND DOSAGE FORMS

The present disclosure relates to pharmaceutical compositions comprising N-[5-(3,5-difluorobenzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-2H-pyran-4-ylamino)-benzamide and a polymer, dosage forms comprising the formulation and methods of treating subjects having cancer. La présen...

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Bibliographische Detailangaben
Hauptverfasser: ORR, Robert, LACHAPELLE, Edward Dennis, PUGH, Kathryn Emily Columbo, UHRIG, Brent Antone, SHAFFER, Matthew Jarud, MCLAUGHLIN, Charlie Michael
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The present disclosure relates to pharmaceutical compositions comprising N-[5-(3,5-difluorobenzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-2H-pyran-4-ylamino)-benzamide and a polymer, dosage forms comprising the formulation and methods of treating subjects having cancer. La présente divulgation concerne des compositions pharmaceutiques comprenant un N-[5-(3,5-difluorobenzyl)-1H-indazol-3-yl]-4-(4-méthyl-pipérazin-1-yl)-2-(tétrahydro-2H-pyran-4-ylamino)-benzamide et un polymère, des formes galéniques comprenant la formulation et des méthodes de traitement de sujets atteints d'un cancer.