METHOD FOR PREPARING APTAMER USING SURROGATE VIRUS

The present invention relates to a method for preparing aptamer by performing modified SELEX, the method comprising a step of bringing a surrogate virus, in which a target protein is expressed on the envelope of the virus, into contact with a nucleic acid library. La présente invention concerne un p...

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Bibliographische Detailangaben
Hauptverfasser:	SHIN, Euisu, JANG, Sung Key, KIM, Kiseok, RYU, Sung Ho, KWON, Junyoung, NARAYAN, Chandan, HAN, Min Jung
Format:	Patent
Sprache:	eng ; fre ; kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a method for preparing aptamer by performing modified SELEX, the method comprising a step of bringing a surrogate virus, in which a target protein is expressed on the envelope of the virus, into contact with a nucleic acid library. La présente invention concerne un procédé de préparation d'aptamère par mise en œuvre d'une méthodologie SELEX modifiée, le procédé comprenant une étape de mise en contact d'un virus de substitution, dans lequel une protéine cible est exprimée sur l'enveloppe du virus, avec une banque d'acides nucléiques. 본 발명은 바이러스의 외피에 표적 단백질이 발현된 대리 바이러스를 핵산 라이브러리에 접촉시키는 단계를 포함하는, 변형된 SELEX를 수행하여 압타머를 제조하는 방법에 관한 것이다.