A NOVEL PROCESS FOR THE PREPARATION OF AN INTERMEDIATE OF ALECTINIB

A NOVEL PROCESS FOR THE PREPARATION OF AN INTERMEDIATE OF ALECTINIB

The present invention provides a novel process for the preparation of 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic acid of Formula (I), (I) which is a key intermediate in the synthesis of Alectinib or its salt of Formula (II). La présente invention concerne un nouveau procédé de préparation d'aci...

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Bibliographische Detailangaben
Hauptverfasser: APPAYE KALIYAPERUMAL, Srinivasan, NANNAPANENI, Venkaiah Chowdary, BUDIDETI, Shankar Reddy, MUDDASANI, Pulla Reddy, TALASANI, Shyam Sunder Reddy, SAMATHAM, Nagalingam, KONDURI, Srinivasa Krishna Murthy
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention provides a novel process for the preparation of 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic acid of Formula (I), (I) which is a key intermediate in the synthesis of Alectinib or its salt of Formula (II). La présente invention concerne un nouveau procédé de préparation d'acide 2-(4-éthyl-3-iodophényl)-2-méthylpropanoïque de formule (I), (I) qui est un intermédiaire clé dans la synthèse d'Alectinib ou de son sel de formule (II).