[6R]-MTHF MULTIPLE BOLUS ADMINISTRATION IN 5-FLUOROURACIL BASED CHEMOTHERAPY
The present invention relates to the treatment of solid tumors in humans such as cancer, especially colorectal cancer (CRC), which involves administering multiple boluses of the diastereomerically pure folate adjuvant [6R]-5,10-methylenetetrahydrofolate in 5-fluorouracil (5-FU) based chemotherapy. L...
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creator | LINDBERG, Per Lennart SUNDÉN, Gunnel Elisabeth GUSTAVSSON, Bengt VEDIN, Anders |
description | The present invention relates to the treatment of solid tumors in humans such as cancer, especially colorectal cancer (CRC), which involves administering multiple boluses of the diastereomerically pure folate adjuvant [6R]-5,10-methylenetetrahydrofolate in 5-fluorouracil (5-FU) based chemotherapy.
La présente invention concerne le traitement de tumeurs solides chez l'homme telles que le cancer, en particulier le cancer colorectal (CRC), qui consiste à administrer de multiples bolus de l'adjuvant de folate diastéréoisomériquement pur qu'est le [6R]-5,10-méthylènetétrahydrofolate au cours d'une chimiothérapie à base de 5-fluoro-uracile (5-FU). |
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La présente invention concerne le traitement de tumeurs solides chez l'homme telles que le cancer, en particulier le cancer colorectal (CRC), qui consiste à administrer de multiples bolus de l'adjuvant de folate diastéréoisomériquement pur qu'est le [6R]-5,10-méthylènetétrahydrofolate au cours d'une chimiothérapie à base de 5-fluoro-uracile (5-FU).</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190228&DB=EPODOC&CC=WO&NR=2019037899A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190228&DB=EPODOC&CC=WO&NR=2019037899A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LINDBERG, Per Lennart</creatorcontrib><creatorcontrib>SUNDÉN, Gunnel Elisabeth</creatorcontrib><creatorcontrib>GUSTAVSSON, Bengt</creatorcontrib><creatorcontrib>VEDIN, Anders</creatorcontrib><title>[6R]-MTHF MULTIPLE BOLUS ADMINISTRATION IN 5-FLUOROURACIL BASED CHEMOTHERAPY</title><description>The present invention relates to the treatment of solid tumors in humans such as cancer, especially colorectal cancer (CRC), which involves administering multiple boluses of the diastereomerically pure folate adjuvant [6R]-5,10-methylenetetrahydrofolate in 5-fluorouracil (5-FU) based chemotherapy.
La présente invention concerne le traitement de tumeurs solides chez l'homme telles que le cancer, en particulier le cancer colorectal (CRC), qui consiste à administrer de multiples bolus de l'adjuvant de folate diastéréoisomériquement pur qu'est le [6R]-5,10-méthylènetétrahydrofolate au cours d'une chimiothérapie à base de 5-fluoro-uracile (5-FU).</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPCJNguK1fUN8XBT8A31CfEM8HFVcPL3CQ1WcHTx9fTzDA4Jcgzx9PdT8PRTMNV18wn1D_IPDXJ09vRRcHIMdnVRcPZw9fUP8XANcgyI5GFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8eH-RgaGlgbG5haWlo6GxsSpAgCfky9O</recordid><startdate>20190228</startdate><enddate>20190228</enddate><creator>LINDBERG, Per Lennart</creator><creator>SUNDÉN, Gunnel Elisabeth</creator><creator>GUSTAVSSON, Bengt</creator><creator>VEDIN, Anders</creator><scope>EVB</scope></search><sort><creationdate>20190228</creationdate><title>[6R]-MTHF MULTIPLE BOLUS ADMINISTRATION IN 5-FLUOROURACIL BASED CHEMOTHERAPY</title><author>LINDBERG, Per Lennart ; SUNDÉN, Gunnel Elisabeth ; GUSTAVSSON, Bengt ; VEDIN, Anders</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2019037899A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2019</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LINDBERG, Per Lennart</creatorcontrib><creatorcontrib>SUNDÉN, Gunnel Elisabeth</creatorcontrib><creatorcontrib>GUSTAVSSON, Bengt</creatorcontrib><creatorcontrib>VEDIN, Anders</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LINDBERG, Per Lennart</au><au>SUNDÉN, Gunnel Elisabeth</au><au>GUSTAVSSON, Bengt</au><au>VEDIN, Anders</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>[6R]-MTHF MULTIPLE BOLUS ADMINISTRATION IN 5-FLUOROURACIL BASED CHEMOTHERAPY</title><date>2019-02-28</date><risdate>2019</risdate><abstract>The present invention relates to the treatment of solid tumors in humans such as cancer, especially colorectal cancer (CRC), which involves administering multiple boluses of the diastereomerically pure folate adjuvant [6R]-5,10-methylenetetrahydrofolate in 5-fluorouracil (5-FU) based chemotherapy.
La présente invention concerne le traitement de tumeurs solides chez l'homme telles que le cancer, en particulier le cancer colorectal (CRC), qui consiste à administrer de multiples bolus de l'adjuvant de folate diastéréoisomériquement pur qu'est le [6R]-5,10-méthylènetétrahydrofolate au cours d'une chimiothérapie à base de 5-fluoro-uracile (5-FU).</abstract><oa>free_for_read</oa></addata></record> |
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subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | [6R]-MTHF MULTIPLE BOLUS ADMINISTRATION IN 5-FLUOROURACIL BASED CHEMOTHERAPY |
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