[6R]-MTHF MULTIPLE BOLUS ADMINISTRATION IN 5-FLUOROURACIL BASED CHEMOTHERAPY

[6R]-MTHF MULTIPLE BOLUS ADMINISTRATION IN 5-FLUOROURACIL BASED CHEMOTHERAPY

The present invention relates to the treatment of solid tumors in humans such as cancer, especially colorectal cancer (CRC), which involves administering multiple boluses of the diastereomerically pure folate adjuvant [6R]-5,10-methylenetetrahydrofolate in 5-fluorouracil (5-FU) based chemotherapy. L...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: LINDBERG, Per Lennart, SUNDÉN, Gunnel Elisabeth, GUSTAVSSON, Bengt, VEDIN, Anders
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention relates to the treatment of solid tumors in humans such as cancer, especially colorectal cancer (CRC), which involves administering multiple boluses of the diastereomerically pure folate adjuvant [6R]-5,10-methylenetetrahydrofolate in 5-fluorouracil (5-FU) based chemotherapy. La présente invention concerne le traitement de tumeurs solides chez l'homme telles que le cancer, en particulier le cancer colorectal (CRC), qui consiste à administrer de multiples bolus de l'adjuvant de folate diastéréoisomériquement pur qu'est le [6R]-5,10-méthylènetétrahydrofolate au cours d'une chimiothérapie à base de 5-fluoro-uracile (5-FU).