NOVEL HETEROCYCLIC COMPOUNDS AS CDK8/19 INHIBITORS

The present invention relates to novel compounds of formula (I), or a pharmaceutically acceptable salt or stereoisomer thereof, which exhibit the properties of a CDK 8/19 inhibitor. The invention also relates to a pharmaceutical composition containing said compounds and to the use thereof as pharmac...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	KASATKINA, Mariia Andreevna, CHESTNOVA, Anna Jur'evna, GORBUNOVA, Svetlana Leonidovna, ZAVIALOV, Kirill Vadimovich, KOZHEMYAKINA, Natalia Vladimirovna, POPKOVA, Aleksandra Vladimirovna, ALAFINOV, Andrei Ivanovich, IAKOVLEV, Pavel Andreevich, KUSHAKOVA, Anna Sergeevna, MOROZOV, Dmitry Valentinovich, MINDICH, Aleksei Leonidovich, SHEKHAUTSOU, Artsiom Evgenievich, ALESHUNIN, Pavel Aleksandrovich, REKHARSKY, Mikhail Vladimirovich, EVDOKIMOV, Anton Aleksandrovich, MAKSIMENKO, Elena Aleksandrovna, MISHINA, Mariia Sergeevna
Format:	Patent
Sprache:	eng ; fre ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to novel compounds of formula (I), or a pharmaceutically acceptable salt or stereoisomer thereof, which exhibit the properties of a CDK 8/19 inhibitor. The invention also relates to a pharmaceutical composition containing said compounds and to the use thereof as pharmaceutical drugs for treating diseases or disorders. La présente invention concerne de nouveaux composés ayant la formule (I) ou leur sel pharmaceutiquement acceptable ou leur stéréoisomère possédant les propriétés de l'inhibiteur CDK8/19, une composition pharmaceutique contenant ces composés et leur utilisation en tant que préparations médicamenteuses pour traiter différentes maladies ou troubles. Настоящее изобретение относится к новым соединениям формулы (I): или его фармацевтически приемлемая соль, или его стереоизомер, которые обладают свойствами ингибитора CDK8/19, к фармацевтической композиции, содержащей данные соединения, и их применению в качестве фармацевтических препаратов для лечения заболеваний или нарушений.