MEDICAL APPLICATION OF COMPOSITION OF FRUCTOSE-1,6-BISPHOSPHATE (FBP) AND PLASMA CONCENTRATION STABILIZER THEREOF

Application of a composition of FBP and a plasma concentration stabilizer thereof in preparing drugs for preventing and treating metabolic diseases and metabolic dysfunction related diseases. The FBP may also be a primary form thereof, and a pharmaceutically acceptable salt and hydrate of a prodrug or derivative thereof. The plasma concentration stabilizer refers to a drug or substance for treating diabetes capable of slowing down rapid in vivo degradation of FBP in a pharmaceutical preparation. The composition can cause a higher FBP plasma concentration peak value and a more stable plasma concentration, and can reduce an FBP dosage and thus can reduce the toxicity resulting from a large amount of inorganic phosphorus entering systemic circulation after degradation of a large dosage of FBP. L'invention concerne l'application d'une composition de FBP et d'un stabilisateur de la concentration plasmatique de cette dernière dans la préparation de médicaments pour la prévention et le traitement de maladies métabol