PROCESS FOR THE PREPARATION OF SUBSTITUTED (1H-1,2,4-TRIAZOL-1-YL)ALCOHOLS

The present invention relates to a process for preparing substituted (1H-1,2,4-triazol-l-yl)alcohols of formula (I), wherein R1, R4, m and Y are defined as disclosed in the specification, by reacting 1H-1,2,4-triazole and oxirane of formula (II), in the presence of a base and polyalkylene glycol. Al...

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Bibliographische Detailangaben
Hauptverfasser:	HEILMANN, Eike Kevin, SCHOTES, Christoph, MEYER, Manfred
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY FISHING FORESTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HUNTING METALLURGY ORGANIC CHEMISTRY PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING
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Beschreibung
Zusammenfassung:	The present invention relates to a process for preparing substituted (1H-1,2,4-triazol-l-yl)alcohols of formula (I), wherein R1, R4, m and Y are defined as disclosed in the specification, by reacting 1H-1,2,4-triazole and oxirane of formula (II), in the presence of a base and polyalkylene glycol. Also disclosed are particular crystalline forms of 2-[6- (4-bromophenoxy)-2-(trifluoromethyl)pyridin-3-yl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol, a compound available by said process. La présente invention concerne un procédé de préparation de (1H-1,2,4-triazol-1-yl)alcools substitués de formule (I), dans laquelle R1, R4, m et Y sont tels que définis dans la description, par réaction de 1H-1,2,4-triazole et d'oxirane de formule (II), en présence d'une base et de polyalkylèneglycol. L'invention concerne également des formes cristallines particulières de 2-[6-(4-bromophénoxy)-2-(trifluorométhyl)pyridin-3-yl]-1-(1H -1,2,4-triazol-1-yl)propan-2-ol, un composé disponible selon ledit procédé.