MODULATORS OF ALPHA-SYNUCLEIN

The disclosure provides diagnostic methods and methods for treatment of conditions arising from alpha-synucleopathies. An aminopyrazole compound can be used for treatment of such conditions by lowering the amount of alpha-synuclein in cells of a subject. L'invention concerne des méthodes de dia...

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Bibliographische Detailangaben
Hauptverfasser:	YOO, Sungeun, LEE, Jae Moon, CHUNG, Yeontae, JANG, Taeik, KIM, Boksuk, YU, Changsun, KIM, Eunhee
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TESTING
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Beschreibung
Zusammenfassung:	The disclosure provides diagnostic methods and methods for treatment of conditions arising from alpha-synucleopathies. An aminopyrazole compound can be used for treatment of such conditions by lowering the amount of alpha-synuclein in cells of a subject. L'invention concerne des méthodes de diagnostic et des méthodes de traitement d'états pathologiques résultant d'alpha-synucléopathies. Un composé d'aminopyrazole peut être utilisé pour le traitement de tels états pathologiques, au moyen d'une réduction de la quantité d'alpha-synucléine dans les cellules d'un sujet.