β-CARBOLINE COMPOUND AND SYNTHETIC METHOD AND APPLICATION THEREOF

Provided are a particular compound of 1-pyridine-6-methoxy-9-(3-methylbenzyl)β-carboline and a synthetic method and application thereof. The compound has significant anti-renal fibrosis activity in vitro and can be used in preparing a drug against renal fibrosis or chronic kidney disease. L'inv...

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Hauptverfasser:	ZHU, Yanhong, PENG, Yan, CHEN, Sheng, LONG, Jingxian, YANG, Yang, ZHANG, Guohai
Format:	Patent
Sprache:	chi ; eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Provided are a particular compound of 1-pyridine-6-methoxy-9-(3-methylbenzyl)β-carboline and a synthetic method and application thereof. The compound has significant anti-renal fibrosis activity in vitro and can be used in preparing a drug against renal fibrosis or chronic kidney disease. L'invention concerne un composé particulier de 1-pyridine-6-méthoxy-9-(3-méthylbenzyl)β-carboline, un procédé de synthèse et une application de celui-ci. Le composé a une activité significative de fibrose anti-rénale in vitro et peut être utilisé dans la préparation d'un médicament contre la fibrose rénale ou une maladie rénale chronique. 提供一种1-吡啶-6-甲氧基-9-(3-甲基苄)β-咔啉的具体化合物及其合成方法和应用。所述化合物具有显著的体外抗肾纤维化活性，可用于制备各种抗肾纤维化、抗慢性肾病药物。